The Mona Lisa without the Mona Lisa
I hope this starts a trend: Artist Mike Ruiz ran the Mona Lisa through Adobe Photoshop CS5’s mindbending content-aware fill tool, which generated its best guess as to what the space behind Mona held. He then sent the resulting image to a Chinese oil painting manufacturer to lay to canvas. This is the result. Art historians will no doubt be interested to learn that there were apparently a lot of shrubberies in the background.
See also: Andy Baio’s viral video backgrounds.