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mice

  1. Even Wild Mice Really Dig Running Around in Wheels

    Treadmills: not just for the chronically lazy anymore!

    When you buy a rodent or small creature as a pet, you're usually encouraged to buy that pet a little wheel—the logic being that they won't get to run around as much inside that tiny cage and will need something to burn off all their extra neurotic rodent energy. But apparently, it's not just captivity-bred animals who find wheels fun.

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  2. National Institute of Health Tells Labs to Stop Ignoring Females in Lab Experiments

    What would Mrs. Frisby have to say about this?

    Science arguably has a problem with gender equality in humans, but it definitely has one in rodents. For decades, researchers have used male mice and rats in laboratory tests instead of females because of concerns their hormones and reproductive cycles would skew results. Well, the National Institutes of Health says knock it off, jerks.

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  3. Lifespan of Mice Increased With Experimental Drug, Prepare for Your Immortal Rodent Overlords

    Nicodemus would be pleased.

    A new experimental drug has shown to increase the lifespan of mice. The drug could have positive implications for humans as well, but let's focus on the real goal here: mice immortality.

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  4. Study Shows Lab Rodents Lose Their Shit Around Men

    At least this is good news for female scientists? Maybe?

    A study published today in Nature is casting doubt on the results of countless pre-clinical trials performed using lab rodents. Researchers through the University of McGill have discovered that mice and rats freak the fuck out in the presence of men—so by the transitive property, I guess I am also a rodent?

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  5. We May Have Found A Way to Turn Off Hunger, And It Involves Lasers

    It's cool, I didn't really want that second burger anyways, you guys.

    If you're interested in losing weight, and aren't afraid of having your brain controlled by a laser beam through your eyeballs, then science has the perfect solution for you! In a recent study (using mice only, at this point), scientists think they've discovered the part of the brain that allows for overeating - and how to turn it off.

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  6. Urine Stem Cells Used to Grow Human Teeth Inside of Mouse Kidneys

    Because sometimes, science is basically a Mad Lib.

    Researchers at the Chinese Academy of Sciences are reporting that using a mix of stem cells and mouse connective tissue, they have successfully grown human teeth inside the kidney of a mouse. If it pans out, the research could have huge implications for dental and implantation technology. If not, it's just another weird thing we can do to mice.

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  7. First Successful Interspecies Cell Transplants Could Pave the Way for Future Pig-to-Human Transplants

    Transplanting insulin producing cells from rats to mice isn't human medicine yet, but it's a hell of a first step.

    Researchers at Northwestern Medicine have successfully transplanted insulin-producing cells across species lines -- removing cells from rats and implanting them in mice -- without using drugs to prevent rejection of the foreign cells. While the transplant may seem like a small victory -- mice and rats are pretty similar, after all -- it marks a significant step forward in interspecies transplants that could one day save human lives by allowing the implantation of insulin-producing "islet" cells without necessitating the use of immunosuppressive drugs that can have dire side effects. 

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  8. Human Liver Buds Successfully Grown From Stem Cells

    The liver buds continue to grow in mouse transplant subjects, suggesting they could one day help to save human lives.

    Researchers at Japan's Yokohama City University have reported in Nature this week that they have used stem cells to create human liver buds that continue to grow and perform the organ's normal functions when transplanted into mice. In experiments, the lab-grown liver-ettes even helped to stave off death in mice suffering from liver failure. Though a preliminary step that may not see practical application for years, this represents a major discovery that shows promise for growing human organs from scratch for use in organ transplants.

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  9. Science Develops Saddest, Weirdest Mouse With Muscles That Light Up as They Break Down

    Today brings us a reminder that genetic engineering can do very strange, very specific things. Researchers studying muscular dystrophy have engineered a mouse model of the disease, but needed a better way to track its progress as the disease ravages their tiny mouse muscles. The solution? Engineer the already muscular dystrophy-prone mice with a gene from fireflies that causes their muscles to glow in relation to how much damage has been done to them by the disease. So those exist now.

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  10. Few Too Many Pounds? Trim Down With Bacteria From Your Buddy’s Gut

    There's always some new "breakthrough" in weight loss, touted by celebrities or TV personalities with pills, programs, or delicious new shakes. But you know what they're not touting, but actually could work? Ingesting the gut bacteria of someone slimmer than you. That's right. A new study finds that if you had the right bacteria transplant, losing weight might not be as much of a problem.

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